Establishing a Biologic Specimens Repository for Reproductive Clinical Trials: Technical Aspects
Year: 2011
Type: article
Abstract: The individual research group or independent investigator often requires access to samples from a unique well characterized subject population. Cohorts of such samples from a well-defined comparative population are rare and limited access can impede progress. This bottleneck can be removed by accessing the samples provided by biorepositories such as the NIH/NICHD Cooperative Reproductive Medicine Network (RMN) Biorepository (detailed in the preceeding manuscript in this issue. In those cases where the individual research group or independent investigator already has access to a unique population, comparisons between well-defined groups are often sought to contextualize the data. In both cases seamless integration of data resources associated with the samples is required to ensure optimal comparisons. At the most basic level this requires standardization of sample collection and storage, as well as a de-identified data base containing demographic, clinical, and laboratory values. To facilitate such interoperability, the reagents and protocols that have been adopted by the RMN Biorepository for the collection and storage of serum, blood, saliva and sperm are described.
Institutions: Wayne State University, University of Vermont, Yale University, Pennsylvania State University, University of Colorado Denver, University of Pennsylvania, The University of Texas at San Antonio Health Science Center, University of Michigan, National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development
Language: English
Subfield: Information Systems
Field: Computer Science
Domain: Physical Sciences
Open Access status: bronze
Awards: GHSU/WSU Cooperative Reproductive Medicine Network, Colorado Reproductive Medicine Unit, Efficacy of Dexamethasone in Polycystic Ovary Syndrome Related Infertility, G3594628407, G4726610437, Data Coordination Center for the RMN, G6773665694, Cooperative Multicenter Reproductive Medicine Network, G745658556, The Utility of Empiric Medical Treatment of Infertile Oligo-asthenospermic Men, A RCT of preconception weight loss vs. OCP in overweight infertile PCOS women, Cooperative Multicenter Reproductive Medicine Network
OpenAlex ID: W2096640352