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Synthesis of New Dihydroindeno[1,2-c]isoquinoline and Indenoisoquinolinium Chloride Topoisomerase I Inhibitors Having High in Vivo Anticancer Activity in the Hollow Fiber Animal Model

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Year: 2001
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/jm000498f
Authors: Muthusamy Jayaraman, Brian M. Fox, Melinda Hollingshead, Glenda Kohlhagen, Yves Pommier, Mark Cushman
Institutions: National Institutes of Health, Purdue University West Lafayette, National Cancer Institute, Center for Cancer Research
Language: English

Topic: Cancer therapeutics and mechanisms
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Cancer Institute
Awards: Novel Indenoisoquinoline Topoisomerase I Inhibitors, G3029148, G5016447163, OPERATIONS &TECHNICAL SUPPORT, G5997445562, Training in Drug and Carcinogen-DNA Interactions
OpenAlex ID: W2096712606
FWCI: 3.04
Cites: 17
Cited by: 94
Related to: 10
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