In Vitro Echinocandin Susceptibility of Aspergillus Isolates from Patients Enrolled in the Transplant-Associated Infection Surveillance Network
Year: 2011
Type: article
Abstract: We determined the echinocandin minimum effective concentration (MEC) values for caspofungin, micafungin, and anidulafungin against 288 Aspergillus isolates prospectively collected from transplant patients with proven or probable invasive aspergillosis between 2001 and 2006 as part of the Transplant-Associated Infection Surveillance Network (TRANSNET). We demonstrated that the vast majority of Aspergillus isolates had MEC values at or below the epidemiological cutoff values for caspofungin, micafungin, and anidulafungin, including those from patients who had received caspofungin.
DOI: 10.1128/aac.00428-11
Institutions: Centers for Disease Control and Prevention, University of Alabama at Birmingham, Birmingham VA Medical Center, Johns Hopkins University, Johns Hopkins Medicine, University of Wisconsin–Madison, NewYork–Presbyterian Hospital, Cornell University, National Cancer Institute, University of Michigan, VA Ann Arbor Healthcare System, Michigan Medicine, Ann Arbor VA Medical Center, The University of Texas MD Anderson Cancer Center, City Of Hope National Medical Center
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2096722233