Work

Facile one-pot synthesis of polymer–phospholipid composite microbubbles with enhanced drug loading capacity for ultrasound-triggered therapy

Year: 2011

Type: article

Abstract: This paper reports the one-pot synthesis of perfluorocarbon microbubbles with crosslinked shells of poly(acrylic acid) and phospholipid that boast excellent ultrasound contrast enhancement, enhanced loading capacity, and the ability to retain or release their contents through variation in the level of ultrasound exposure.

Source: Soft Matter

DOI: 10.1039/c0sm01131b

Authors: Matthew A. Nakatsuka, Joo Hye Lee, Emi Nakayama, Albert M. Hung, Mark J. Hsu, Robert F. Mattrey, Sadik C. Esener, Jennifer N. Cha, Andrew P. Goodwin

Institution: University of California San Diego

Language: English

Topic: Ultrasound and Hyperthermia Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute

Awards: G2881053379, Center of Nanotechnology for Treatment, Understanding, *, Enzyme-Responsive Nanoemulsions as Tumor-Specific Ultrasound Contrast Agents for, In Vivo Cellular and Molecular Imaging Centers (ICMICs), UCSD Cancer Center Training Program in Drug Development

OpenAlex ID: W2097500380

FWCI: 1.513

Cites: 28

Cited by: 20

Related to: 10