‘Someday it will be the Norm’: Physician Perspectives on the Utility of Genome Sequencing for Patient Care in the Medseqproject
Year: 2015
Type: article
Abstract: AIM: To describe practicing physicians' perceived clinical utility of genome sequencing. MATERIALS & METHODS: We conducted a mixed-methods analysis of data from 18 primary care physicians and cardiologists in a study of the clinical integration of whole-genome sequencing. Physicians underwent brief genomics continuing medical education before completing surveys and semi-structured interviews. RESULTS: Physicians described sequencing as currently lacking clinical utility because of its uncertain interpretation and limited impact on clinical decision-making, but they expressed the idea that its clinical integration was inevitable. Potential clinical uses for sequencing included complementing other clinical information, risk stratification, motivating patient behavior change and pharmacogenetics. CONCLUSION: Physicians given genomics continuing medical education use the language of both evidence-based and personalized medicine in describing the utility of genome-wide testing in patient care.
Source: Personalized Medicine
DOI: 10.2217/pme.14.68
Language: English
Topic: Genomics and Rare Diseases
Subfield: Genetics
Domain: Life Sciences
Open Access status: green
Awards: Incidental Finding Preferences in Whole Genome Sequencing: A Randomized Trial, Harvard Clinical and Translational Science Center (UL1), G4247737171, Genome Sequence-Based Screening for Childhood Risk and Newborn Illness, G5950995486, Integration of Whole Genome Sequencing into Clinical Medicine
OpenAlex ID: W2097728451