Walled-off pancreatic necrosis: where are we?
Year: 2014
Type: article
Abstract: Walled-off pancreatic necrosis (WOPN) is a well-circum-scribed area of necrosis which occurs as a late complication of acute pancreatitis, generally after four weeks from the initial attack. The term “walled-off necrosis ” was introduced for the first time in 2006. Approximately 15 % of patients with severe acute pancreatitis will develop a WOPN [1]. The impact of the onset of pancreatic necrosis and other complications after an episode of acute pancreatitis may have deep repercussions on the quality of life of the single patient that can persist for years or even lifelong. For instance, exocrine and endocrine insufficiency following pancreatic necrosis may cause lifelong morbidity. Exocrine and endocrine insufficiency is probably related to the extent of necrosis into the pancreatic parenchyma, or as recently suggested by Rana et al, by the type of approach [2] adopted to clean the necrosis: surgery versus endoscopy.
Source: Europe PMC (PubMed Central)
Authors: Ivo Boškoski, Guido Costamagna
Institution: Università Cattolica del Sacro Cuore
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2097770444