Work

Pet191 Is a Cytochrome c Oxidase Assembly Factor in Saccharomyces cerevisiae

Year: 2008

Type: article

Abstract: The twin-Cx(9)C motif protein Pet191 is essential for cytochrome c oxidase maturation. The motif Cys residues are functionally important and appear to be present in disulfide linkages within a large oligomeric complex associated with the mitochondrial inner membrane. The import of Pet191 differs from that of other twin-Cx(9)C motif class of proteins in being independent of the Mia40 pathway.

Source: Eukaryotic Cell

DOI: 10.1128/ec.00132-08

Authors: Oleh Khalimonchuk, Kevin Rigby, Megan Bestwick, Fabien Pierrel, Paul A. Cobine, Dennis R. Winge

Institution: University of Utah

Language: English

Topic: Mitochondrial Function and Pathology

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: diamond

Funder: National Institute of Environmental Health Sciences

Awards: Assembly of Redox Metal Centers in Cytochrome Oxidase, G4466249638, METAL CHELATION IN PROTEINS WITH POLYMETALLIC CLUSTERS