Work

Supramolecular filaments containing a fixed 41% paclitaxel loading

Year: 2013

Type: article

Abstract: We report here the self-assembly of a rationally designed paclitaxel drug amphiphile into well-defined supramolecular filaments that possess a fixed 41% paclitaxel loading. These filaments can exert effective cytotoxicity against a number of cell lines comparable to that of free paclitaxel.

Source: Chemical Communications

DOI: 10.1039/c3cc41896k

Authors: Ran Lin, Andrew G. Cheetham, Pengcheng Zhang, Yi-an Lin, Honggang Cui

Institution: Johns Hopkins University

Language: English

Topic: Supramolecular Self-Assembly in Materials

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute