Thirty years of intracrinology.
Year: 2014
Type: article
Abstract: BACKGROUND: Intracrinology is the study of the intracellular actions, regulation, trafficking, and interactions of extracellular signaling peptides/proteins. METHODS: We describe the development of intracrine biology since the term was defined in 1984. RESULTS: Intracrine biology plays a role in many normal and pathological processes and represents a fertile field for the development of novel therapeutics. CONCLUSION: Although 30 years old, the field of intracrinology is only now becoming widely accepted. Intracrine principles can be applied to the investigation of physiological processes and to the development of new therapies.
Source: PubMed Central
Author: Richard N Re
Institution: Ochsner Health System
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2098063028