Work

Genomic Relatedness of the New Matlab Variants of Vibrio cholerae O1 to the Classical and El Tor Biotypes as Determined by Pulsed-Field Gel Electrophoresis

Year: 2005

Type: article

Abstract: The genomes of the recently described Matlab variants of Vibrio cholerae O1 that are hybrids between classical and El Tor biotypes were compared with those of El Tor and classical biotypes by the use of pulsed-field gel electrophoresis. Dendrograms constructed using the unweighted-pair group method using average linkages generated from NotI restriction patterns of whole-chromosomal DNA grouped these strains into two major clusters that were found to be similar but not identical to those of either of the biotypes. Strains that clustered with the classical biotype appear to have been derived from the classical strains, which are thought to be extinct.

Source: Journal of Clinical Microbiology

DOI: 10.1128/jcm.43.3.1401-1404.2005

Authors: Ashrafus Safa, Nurul Amin Bhuiyan, Munirul Alam, David A. Sack, G. Balakrish Nair

Institution: International Centre for Diarrhoeal Disease Research

Language: English

Topic: Vibrio bacteria research studies

Subfield: Endocrinology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Allergy and Infectious Diseases