Work

Chlamydiae Modulate Gamma Interferon, Interleukin-1β, and Tumor Necrosis Factor Alpha Receptor Expression in HeLa Cells

Year: 2006

Type: article

Abstract: Chlamydia psittaci was found to modulate receptor expression for the cytokine receptors that are involved in the synergistic induction of indoleamine dioxygenase in epithelial cells. Increases in receptor expression were seen even with inactivated Chlamydia, suggesting that chlamydial antigens and not products of infection are important for up-regulating cytokine receptor expression.

Source: Infection and Immunity

DOI: 10.1128/iai.74.4.2482-2486.2006

Authors: Kari Ann Shirey, Joseph M. Carlin

Institution: Miami University

Language: English

Topic: Immune Response and Inflammation

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: University of Miami, National Institute of Allergy and Infectious Diseases