Work

Modeling complex neuropsychiatric disease with induced pluripotent stem cells

Year: 2010

Type: article

Abstract: The study of neuropsychiatric diseases and the development of effective treatments have been limited by a lack of appropriate models. Induced pluripotent stem cells (iPSCs) represent a potentially limitless supply of patient-specific cells for the study of neuropsychiatric disorders. In this review, we will discuss the potential and limitations of iPSCs for the development of cell-based models of neuropsychiatric diseases and the identification of novel therapeutics.

Source: F1000 Biology Reports

DOI: 10.3410/b2-84

Authors: P Joel Ross, James Ellis

Institutions: Hospital for Sick Children, University of Toronto

Language: English

Topic: Pluripotent Stem Cells Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: National Institute of Mental Health