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False-positive serologic test resulting from a probable yeast infection in a chimpanzee

Year: 1996

Type: article

Abstract: Sera used to identify putative hepatitis E viral proteins expressed in Pischia pastoris produced a false-positive reaction because of antibodies to a yeast protein. This report illustrates a potential problem when serological reagents are used in combination with recombinant proteins expressed in yeast.

Source: Clinical and Diagnostic Laboratory Immunology

DOI: 10.1128/cdli.3.5.614-615.1996

Authors: T Heller, S Yin, S A Tsarev, R H Purcell, S U Emerson

Institutions: National Institutes of Health, National Institute of Allergy and Infectious Diseases

Language: English

Topic: Hepatitis Viruses Studies and Epidemiology

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2098523080

FWCI:

Cites: 1

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Related to: 10