Work

Molecular and Immunological Analyses of the Borrelia turicatae Bdr Protein Family

Year: 2000

Type: article

Abstract: Here, we describe the molecular and immunological characterization of the bdr gene family of Borrelia turicatae, a relapsing-fever spirochete. Nine bdr alleles belonging to two different subfamilies were sequenced and localized to linear plasmids. Anti-Bdr antiserum was generated and used to analyze Bdr expression in pre- and postinfection isogenic populations. The analyses presented here provide a detailed characterization of the Bdr proteins in a relapsing-fever spirochete species, enhancing our understanding of these proteins at the genus-wide level.

Source: Infection and Immunity

DOI: 10.1128/iai.68.4.2369-2373.2000

Authors: Jason A. Carlyon, David M. Roberts, Michael Theisen, Christina Sadler, Richard T. Marconi

Institutions: Virginia Commonwealth University, Virginia Commonwealth University Medical Center, Statens Serum Institut, Mary Baldwin University

Language: English

Topic: Vector-borne infectious diseases

Subfield: Parasitology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2098761360

FWCI: 2.324

Cites: 27

Cited by: 16

Related to: 10