Work

Polymer nanoparticles for drug and small silencing RNA delivery to treat cancers of different phenotypes

Year: 2013

Type: review

Abstract: Advances in nanotechnology have provided powerful and efficient tools in the development of cancer diagnosis and therapy. There are numerous nanocarriers that are currently approved for clinical use in cancer therapy. In recent years, biodegradable polymer nanoparticles have attracted a considerable attention for their ability to function as a possible carrier for target‐specific delivery of various drugs, genes, proteins, peptides, vaccines, and other biomolecules in humans without much toxicity. This review will specifically focus on the recent advances in polymer‐based nanocarriers for various drugs and small silencing RNA's loading and delivery to treat different types of cancer. WIREs Nanomed Nanobiotechnol 2014, 6:40–60. doi: 10.1002/wnan.1242 This article is categorized under: Therapeutic Approaches and Drug Discovery > Nanomedicine for Oncologic Disease

Source: Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology

DOI: 10.1002/wnan.1242

Authors: Rammohan Devulapally, Ramasamy Paulmurugan

Institutions: Stanford Medicine, Stanford University

Language: English

Topic: Nanoparticle-Based Drug Delivery

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute