Work

Bioorthogonal oxime ligation mediated in vivo cancer targeting

Year: 2015

Type: article

Abstract: cancer targeting of PEG-PLA NPs is achieved through specific and efficient chemical reaction between the oxyamine and aldehyde groups.

Source: Chemical Science

DOI: 10.1039/c5sc00063g

Authors: Li Tang, Qian Yin, Yunxiang Xu, Qin Zhou, Kaimin Cai, Jonathan Yen, Lawrence W. Dobrucki, Jianjun Cheng

Institutions: University of Illinois Urbana-Champaign, Guangdong Pharmaceutical University

Language: English

Topic: Click Chemistry and Applications

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: National Science Foundation, National Institutes of Health, University of Illinois at Urbana-Champaign, National Cancer Institute, Division of Materials Research

Awards: Responsive Drug-Polymer Conjugate, G295795756, Training the Next Generation of Researchers in Cancer Nanotechnology at the NCI M, Developing Clinically Applicable, Cancer-Targeting Polymeric Nanoconjugates, G4778635926, G7392520601

OpenAlex ID: W2099085779

FWCI: 2.132

Cites: 47

Cited by: 33

Related to: 10