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Abstract A71: Basal- and treatment-induced activation of the PI3K-AKT pathway are critical determinants of the efficacy of the MEK inhibitor AZD6244 (ARRY-142886) in melanoma

Year: 2009

Type: conference-abstract

Source: Molecular Cancer Therapeutics

DOI: 10.1158/1535-7163.targ-09-a71

Authors: Vashisht G. Yennu-Nanda, Wanleng Deng, Paul D. Smith, Michael A. Davies

Institutions: The University of Texas MD Anderson Cancer Center, AstraZeneca (United Kingdom)

Language: English

Topic: Melanoma and MAPK Pathways

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W2099516828

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