Work

Essential Elements to Consider for MRI Cell Tracking Studies with Iron Oxide-based Labeling Agents.

Year: 2012

Type: article

Abstract: visualization of the labeled cells, some critical elements for cell tracking studies are often incompletely characterized, which makes it difficult to validate and meta-analyze the data generated from different studies. Incomplete information on preclinical studies also slows the transition of the findings to clinical practice. A robust protocol of MRI cell tracking studies is apparently critical to deal with these issues. In this review, we first briefly discuss the limitations of MRI cell tracking based on iron oxide nanoparticles and then recommend a minimum set of essential elements that should be considered in MRI cell tracking studies at preclinical stage.

Source: PubMed

Authors: Paul C Wang, Liang Shan

Institution: Howard University

Language: English

Topic: Characterization and Applications of Magnetic Nanoparticles

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Center for Research Resources, National Institute on Minority Health and Health Disparities

Awards: Computational Biology, Bioinformatics, Imaging & Proteomics Research-RCMI, Biomedical Infrastructure for Health Disparities Research