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Optimizing Wnt-3a and R-spondin1 concentrations for stem cell renewal and differentiation in intestinal organoids using a gradient-forming microdevice

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Year: 2015
Type: article
Source: RSC Advances
DOI: 10.1039/c5ra14923a
Authors: Asad A. Ahmad, Yuli Wang, Christopher E. Sims, Scott T. Magness, Nancy L. Allbritton
Institutions: North Carolina State University, University of North Carolina at Chapel Hill
Language: English

Topic: Wnt/β-catenin signaling in development and cancer
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences

Open Access status: closed

Funders: National Institutes of Health, National Eye Institute, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases
Awards: Generation of a Gene-Targeted Human iPS Cell Library for Macular Degeneration, Genetic Control of Intestinal Epithelial Stem Cell Maintenance & Differentiation, Studying Colonic Stem-Cell Niche Using Microengineered Gradient-Generating Device
OpenAlex ID: W2100433842
FWCI: 0.868
Cites: 43
Cited by: 12
Related to: 10
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