Work

Feasibility of cell therapy in multiple sclerosis: a systematic review of 83 studies.

Year: 2013

Type: article

Abstract: Multiple Sclerosis is an inflammatory disease of the central nervous system in which T cells experience a second phase of activation, which ultimately leads to axonal demyelination and neurological disability. The recent advances in stem cell therapies may serve as potential treatments for neurological disorders. There are broad types of stem cells such as neural, embryonic, mesenchymal and hematopoietic stem cells with unprecedented hope in treating many debilitating diseases. In this paper we will review the substantial literature regarding experimental and clinical use of these stem cells and possible mechanisms in the treatment of MS. These results may pave the road for the utilization of stem cells for the treatment of MS.

Source: Europe PMC (PubMed Central)

Authors: Abdolreza Ardeshiry Lajimi, Majid Farshdousti Hagh, Najmaldin Saki, Esmaeil Mortaz, Masoud Soleimani, Fakher Rahim

Institutions: Stem Cell Technology Research Center, Tabriz University of Medical Sciences, Ahvaz Jundishapur University of Medical Sciences, Utrecht University, Tarbiat Modares University

Language: English

Topic: Multiple Sclerosis Research Studies

Subfield: Clinical Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2100546793

FWCI: 3.164

Cites: 172

Cited by: 36

Related to: 10