Work

Reactions Templated by Nucleic Acids: More Ways to Translate Oligonucleotide‐Based Instructions into Emerging Function

Year: 2013

Type: review

Abstract: The programmability of oligonucleotide recognition offers an attractive platform to direct the assembly of reactive partners that can engage in chemical reactions. Recently, significant progress has been made in both the breadth of chemical transformations and in the functional output of the reaction. Herein we summarize these recent progresses and illustrate their applications to translate oligonucleotide instructions into functional materials and novel architectures (conductive polymers, nanopatterns, novel oligonucleotide junctions); into fluorescent or bioactive molecule using cellular RNA; to interrogate secondary structures or oligonucelic acids; or a synthetic oligomer.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.201208460

Authors: Katarzyna Gorska, Nicolas Winssinger

Institutions: University of Geneva, Centre National de la Recherche Scientifique, Institut de Science et d'Ingénierie Supramoléculaires, Université de Strasbourg

Language: English

Topic: Advanced biosensing and bioanalysis techniques

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2100759999

FWCI: 1.518

Cites: 171

Cited by: 159

Related to: 10