Work

Comparison of Lipid Amphotericin B Preparations in Treating Murine Zygomycosis

Year: 2008

Type: article

Abstract: We compared the efficacies of liposomal amphotericin B (LAmB) and an amphotericin B lipid complex (ABLC) in diabetic ketoacidotic (DKA) or neutropenic mice with disseminated zygomycosis. ABLC was as effective as LAmB in neutropenic but not DKA mice. Low-dose ABLC was less effective than LAmB at reducing brain fungal burdens in both models.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.01488-07

Authors: Ashraf S. Ibrahim, Teclegiorgis Gebremariam, Mohamed I. Husseiny, David A. Stevens, Yue Fu, John E. Edwards, Brad Spellberg

Institutions: University of California, Los Angeles, The Lundquist Institute, Los Angeles Medical Center, Harbor–UCLA Medical Center, Santa Clara Valley Medical Center, Stanford Medicine, Stanford University

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Allergy and Infectious Diseases

Awards: Adrenergic Antagonism During Murine Candidiasis, Novel Antifungal Strategies for Lethal Mucormycosis, Novel Toxins and Receptors in Mucormycosis Pathogenesis and Treatment

OpenAlex ID: W2101046576

FWCI: 3.64

Cites: 13

Cited by: 65

Related to: 10