Work

Characterization of reticulocyte release factor.

Year: 1977

Type: article

Abstract: The release factor (RF) of reticulocytes has been purified to greater than 75% homogeneity. The RF has a native molecular weight of 105,000 and subunit molecular weight of 56,500. The RF protein will bind to reticulocyte ribosomes in response to UAAA, UAGA, or UGAA and therefore participates in codon recognition. The fraction possess a ribosome-dependent GTPase activity. The RF is stimulated in its activity by a second protein fraction.

Source: Journal of Biological Chemistry

DOI: 10.1016/s0021-9258(17)40191-8

Authors: D S Konecki, K C Aune, W Tate, C T Caskey

Institutions: Texas Medical Center, Baylor College of Medicine

Language: English

Topic: RNA and protein synthesis mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $3,430

OpenAlex ID: W2101908148

FWCI: 0.768

Cites: 36

Cited by: 110

Related to: 10