Work

In Vitro Efficacy of a Novel Active-Release Antimicrobial Coating To Eradicate Biofilms of Pseudomonas aeruginosa

Year: 2014

Type: article

Abstract: Implant-related infections are becoming increasingly difficult to treat due to the formation of biofilms on implant surfaces. This study analyzed the in vitro efficacy of a novel antimicrobial coating against biofilms of Pseudomonas aeruginosa, using a flow cell system. Results indicated that P. aeruginosa biofilms were reduced by greater than 8 log10 units in less than 24 h. Data indicated that this active-release coating may be promising for preventing biofilm implant-related infections.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.01798-13

Authors: Dustin L. Williams, Julia M. Lerdahl, Bryan S. Haymond, Roy D. Bloebaum

Institutions: University of Utah, George E. Wahlen Department of VA Medical Center

Language: English

Topic: Bacterial biofilms and quorum sensing

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Veterans Affairs, Office of Research and Development, National Institutes of Health, National Institute of Arthritis and Musculoskeletal and Skin Diseases