Work

Streptomyces coelicolor Undergoes Spontaneous Chromosomal End Replacement

Year: 2007

Type: article

Abstract: We report a previously unobserved form of genetic instability for Streptomyces coelicolor, the replacement of one chromosome end by the other end. These genetic changes occurred spontaneously in both a wild-type strain and strains harboring a foreign transposon. Deleted and duplicated DNA comprises up to 33% of the genome.

Source: Journal of Bacteriology

DOI: 10.1128/jb.01049-07

Authors: Elizabeth M. Widenbrant, Hsiu-Hui Tsai, Carton W. Chen, Camilla M. Kao

Institutions: Stanford University, National Yang Ming University

Language: English

Topic: Bacterial Genetics and Biotechnology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: National Science Council

Award: G7996248560