Work

Identification of srv , a PrfA-Like Regulator of Group A Streptococcus That Influences Virulence

Year: 2004

Type: article

Abstract: We have identified a Crp/Fnr-like transcriptional regulator of Streptococcus pyogenes that when inactivated attenuates virulence. The gene, named srv for streptococcal regulator of virulence, encodes a 240-amino-acid protein with 53% amino acid similarity to PrfA, a transcriptional activator of virulence in Listeria monocytogenes.

Source: Infection and Immunity

DOI: 10.1128/iai.72.3.1799-1803.2004

Authors: Sean D. Reid, Alison G. Montgomery, James M. Musser

Institutions: National Institutes of Health, National Institute of Allergy and Infectious Diseases, Rocky Mountain Laboratories

Language: English

Topic: Streptococcal Infections and Treatments

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2103205475

FWCI: 2.027

Cites: 36

Cited by: 29

Related to: 10