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CATIE and CUtLASS: can we handle the truth?

Year: 2008

Type: editorial

Abstract: Two large, non-commercial clinical trials comparing first- and second-generation antipsychotic drugs for people with chronic schizophrenia in the US and UK have shown unexpected results. In general, the newer drugs were no more effective or better tolerated than the older drugs. Clozapine outperformed other second-generation drugs. The implications are considered.

Source: The British Journal of Psychiatry

DOI: 10.1192/bjp.bp.107.037218

Authors: Shôn Lewis, Jeffrey Lieberman

Institutions: University of Manchester, NewYork–Presbyterian Hospital, Columbia University Irving Medical Center, New York State Psychiatric Institute, Columbia University

Language: English

Topic: Schizophrenia research and treatment

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2103205725

Cites: 19

Cited by: 147

Related to: 10