Nanostructure-Initiator Mass Spectrometry Metabolite Analysis and Imaging

Year: 2010

Type: other

Abstract: Nanostructure-Initiator Mass Spectrometry (NIMS) is a matrix-free desorption/ionization approach that is particularly well-suited for unbiased (untargeted) metabolomics. An overview of the NIMS technology and its application in the detection of biofluid and tissue metabolites are presented. (To listen to a podcast about this feature, please go to the Analytical Chemistry multimedia page at pubs.acs.org/page/ancham/audio/index.html .).

Source: Analytical Chemistry

DOI: 10.1021/ac101565f

Authors: Matthew P. Greving, Gary J. Patti, Gary Siuzdak

Institution: Scripps Research Institute

Language: English

Topic: Mass Spectrometry Techniques and Applications

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: U.S. Department of Energy, California Institute of Regenerative Medicine, National Institutes of Health, National Institute for Materials Science, National Institute on Aging, National Institute of Mental Health, National Institute on Drug Abuse, National Eye Institute

OpenAlex ID: W2103762254