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Coronary Abnormalities in Hyper-IgE Recurrent Infection Syndrome: Depiction at Coronary MDCT Angiography

Year: 2009
Type: article
Abstract: OBJECTIVE: Hyper-IgE recurrent infection syndrome (HIES or Job's syndrome) is a rare disorder affecting the immune system and connective tissues. The purpose of this study is to describe the coronary abnormalities in genetically confirmed HIES patients as depicted by coronary MDCT angiography (MDCTA). CONCLUSION: Coronary MDCTA has provided an opportunity for noninvasive evaluation of the coronary arteries in patients with HIES. These coronary abnormalities vary from tortuosity to ectatic dilation and focal aneurysms of the coronary arteries. Such an evaluation has potential value in identifying new aspects of this disease and thereby providing better understanding of the pathophysiology of the disorder.
DOI: 10.2214/ajr.09.2623
Authors: Ahmed M. Gharib, Roderic I. Pettigrew, Abdalla Elagha, Amy Hsu, Pam Welch, Steven M. Holland, Alexandra F. Freeman
Institutions: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health Clinical Center, National Institute of Biomedical Imaging and Bioengineering, National Institute of Allergy and Infectious Diseases, National Cancer Institute
Language: English
Subfield: Immunology
Open Access status: green
OpenAlex ID: W2104243235
FWCI: 0.863
Cites: 14
Cited by: 19
Related to: 10