Work

Nanopatterned collagen tubes for vascular tissue engineering

Year: 2008

Type: article

Abstract: Nanopatterned (330 nm wide channels) type I collagen films were prepared by solvent casting on poly(dimethyl siloxane) (PDMS) templates. These films were rolled into tubular constructs and crosslinked. Tubular constructs were incubated under cell culture conditions for 28 days and examined by stereomicroscopy and scanning electron microscopy (SEM) for the integrity of the structure. The nanopatterned films were also seeded with human vascular smooth muscle cells (VSMCs) and examined after immunostaining with fluorescence microscopy and SEM to assess the cell phenotype and alignment on the nanopatterns on the films.

Source: Journal of Tissue Engineering and Regenerative Medicine

DOI: 10.1002/term.99

Authors: P. Zorlutuna, N. Hasirci, V. Hasirci

Institution: Middle East Technical University

Language: English

Topic: Tissue Engineering and Regenerative Medicine

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2104248974

FWCI: 3.514

Cites: 18

Cited by: 23

Related to: 10