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Methodological Issues in Clinical Drug Development for Essential Tremor

Year: 2011

Type: article

Abstract: Essential tremor (ET) is one of the most common tremor disorders in the world. Despite this, only two medications have received Level A recommendations from the American Academy of Neurology to treat it (primidone and propranolol). Even though these medications provide relief to a large group of ET patients, up to 50% of patients are non-responders. Additional medications to treat ET are needed. This review discusses some of the methodological issues that should be addressed for quality clinical drug development in ET.

Source: Europe PMC (PubMed Central)

DOI: 10.7916/d8p55m7f

Authors: Carranza, Michael A., Snyder, Madeline R., Elble, Rodger J., Boutzoukas, Angelique E., Zesiewicz, Theresa A.

Institution: University of South Florida

Language: English

Topic: Neurological disorders and treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2104340752

FWCI: 0.203

Cites: 40

Cited by: 7

Related to: 10