High-Level Vancomycin-Resistant Staphylococcus aureus (VRSA) in Iran: A Systematic Review
Year: 2013
Type: article
Study design: Systematic Review
Abstract: Background: Staphylococcus aureus is a major human pathogen worldwide. Vancomycin has been used for decades to treat multidrug resistant S. aureus. Ten years has passed since the first report of vancomycin resistant S. aureus (VRSA). The objective of this systematic review was to determine the total number of VRSA isolates that have been reported from Iran. Methods: Search terms reflected “Iran”, “vancomycin” and “S. aureus” were searched in the ISI web of knowledge, PubMed, SciVerse, and Google scholar. Also two Persian scientific databases and 13 recent national congresses were investigated. Articles / abstracts working on S. aureus in Iran, evaluating vancomycin MIC and/or PCR of vanA/B were included in this systematic review. Results: Out of the 3484 records found in mentioned resources, 13 related studies were included in the final analysis. The result showed that at least 24 VRSA isolates which have been reported from Iran up to September 2012. Conclusion: It seems that many Iranian researchers did not follow a specific guideline for reporting and confirming VRSA. Establishing an Iranian reference center where studies on VRSA can be registered, evaluated and confirmed is strongly recommended.
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2104655894