Work

Variation of electrophoretic karyotypes among clinical isolates of Candida albicans

Year: 1988

Type: article

Abstract: Orthogonal-field-alternation gel electrophoresis was used to compare clinical isolates of Candida albicans by resolving chromosome-sized DNA molecules into an electrophoretic karyotype. Seven to nine bands were observed among isolates recovered from 17 patients. In addition, 14 distinct electrophoretic patterns were noted among the isolates from these patients. In a given individual, isolates were likely to have identical electrophoretic patterns. Therefore, the electrophoretic karyotype patterns demonstrated by orthogonal-field-alternation gel electrophoresis can be used to designate a strain for epidemiologic studies.

Source: Journal of Clinical Microbiology

DOI: 10.1128/jcm.26.5.842-845.1988

Authors: W G Merz, C Connelly, P Hieter

Institutions: Johns Hopkins University, Johns Hopkins Medicine

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Cancer Institute