Work

Lateral flow (immuno)assay: its strengths, weaknesses, opportunities and threats. A literature survey

Year: 2008

Type: article

Abstract: Lateral flow (immuno)assays are currently used for qualitative, semiquantitative and to some extent quantitative monitoring in resource-poor or non-laboratory environments. Applications include tests on pathogens, drugs, hormones and metabolites in biomedical, phytosanitary, veterinary, feed/food and environmental settings. We describe principles of current formats, applications, limitations and perspectives for quantitative monitoring. We illustrate the potentials and limitations of analysis with lateral flow (immuno)assays using a literature survey and a SWOT analysis (acronym for "strengths, weaknesses, opportunities, threats"). Articles referred to in this survey were searched for on MEDLINE, Scopus and in references of reviewed papers. Search terms included "immunochromatography", "sol particle immunoassay", "lateral flow immunoassay" and "dipstick assay".

Source: Analytical and Bioanalytical Chemistry

DOI: 10.1007/s00216-008-2287-2

Authors: Geertruida A. Posthuma-Trumpie, Jakob Korf, Aart van Amerongen

Institutions: University Medical Center Groningen, University of Groningen, Wageningen University & Research

Language: English

Topic: Biosensors and Analytical Detection

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $3,990

Funder: Stichting voor de Technische Wetenschappen