Work

Silk Fibroin Microfluidic Devices

Year: 2007

Type: article

Abstract: Microfluidic devices were fabricated from silk fibroin using an aqueous molding process adapted from soft lithography. The process results in mechanically robust, patent devices with macroscopic fluidic connections. Hepatocytes were seeded in the device and perfused for up to five days during which they exhibited liver-specific functions equivalent to that observed for standard tissue culture substrates.

Source: Advanced Materials

DOI: 10.1002/adma.200602487

Authors: C. J. Bettinger, K. M. Cyr, A. Matsumoto, R. Langer, J. T. Borenstein, D. L. Kaplan

Institutions: Draper Laboratory, Massachusetts Institute of Technology, Tufts University

Language: English

Topic: Silk-based biomaterials and applications

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of Dental and Craniofacial Research

Awards: G3085841307, Novel Polymers for Tissue Engineering