Work

Mechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein Processing

Year: 2013

Type: article

Source: Drug Metabolism and Disposition

DOI: 10.1124/dmd.112.050864

Authors: Xingrong Liu, Harvey Wong, Kimberly Scearce-Levie, Ryan J Watts, Melis Coraggio, Young G Shin, Kun Peng, Kristin R Wildsmith, Jasvinder K Atwal, Jason Mango, Stephen P Schauer, Kelly Regal, Kevin W Hunt, Allen A Thomas, Michael Siu, Joseph Lyssikatos, Gauri Deshmukh, Cornelis E. C. A Hop

Institutions: Genentech, Array BioPharma (United States)

Language: English

Topic: Alzheimer's disease research and treatments

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W2106477295

FWCI: 1.853

Cites: 41

Cited by: 18

Related to: 10