Work

Detection of NDM-1-Producing Klebsiella pneumoniae in Kenya

Year: 2010

Type: article

Abstract: Seven carbapenem-resistant NDM-1-positive Klebsiella pneumoniae isolates were recovered from patients hospitalized between 2007 and 2009 in different wards at a referral and tertiary care center in Nairobi. Most of the isolates were obtained from urine. All isolates carried the bla(NDM-1) carbapenemase gene previously reported from India, Pakistan, and the United Kingdom. These isolates were clonally related and expressed many other resistance determinants, including β-lactamases CTX-M-15, OXA-1, OXA-9, CMY-6, and aminoglycoside resistance methylase RmtC. This work corresponds to the first report of NDM-1 producers in Africa.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.01247-10

Authors: Laurent Poirel, Gunturu Revathi, Sandrine Bernabeu, Patrice Nordmann

Institutions: Inserm, Assistance Publique – Hôpitaux de Paris, Bicêtre Hospital, Aga Khan University Hospital Nairobi, Aga Khan University Nairobi

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Microbiology (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: Institut National de la Santé et de la Recherche Médicale