Work

MSnbase-an R/Bioconductor package for isobaric tagged mass spectrometry data visualization, processing and quantitation

Year: 2011

Type: article

Abstract: UNLABELLED: MSnbase is an R/Bioconductor package for the analysis of quantitative proteomics experiments that use isobaric tagging. It provides an exploratory data analysis framework for reproducible research, allowing raw data import, quality control, visualization, data processing and quantitation. MSnbase allows direct integration of quantitative proteomics data with additional facilities for statistical analysis provided by the Bioconductor project. AVAILABILITY: MSnbase is implemented in R (version ≥ 2.13.0) and available at the Bioconductor web site (http://www.bioconductor.org/). Vignettes outlining typical workflows, input/output capabilities and detailing underlying infrastructure are included in the package.

Source: Bioinformatics

DOI: 10.1093/bioinformatics/btr645

Authors: Laurent Gatto, Kathryn S. Lilley

Institution: University of Cambridge

Language: English

Topic: Advanced Proteomics Techniques and Applications

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

Funders: European Commission, Biotechnology and Biological Sciences Research Council

Awards: G1192527504, Proteomics Research Infrastructure Maximising knowledge EXchange and access (XS), Toolkit for Interpretation of Organelle Proteomics Data, Pipeline for interpretation and storage of organelle proteomics data