Work

Autoimmune type 1 diabetes: resolved and unresolved issues

Year: 2001

Type: article

Abstract: Autoimmune diseasesType 1 diabetes, also known as either juvenile diabetes (because of the early age of onset) or insulin-dependent diabetes mellitus (because of the clinical need for insulin), is now widely thought to be an organ-specific autoimmune disease.Here we wish to summarize some generally accepted facts about this disease and then give our perspectives on unresolved issues surrounding prediction, pathogenesis, and treatment.In particular, we will discuss markers of the disease, such as autoantibodies against pancreatic islet cell antigens.

Source: Journal of Clinical Investigation

DOI: 10.1172/jci14257

Authors: Abner Louis Notkins, Åke Lernmark

Institutions: National Institutes of Health, National Institute of Dental and Craniofacial Research, University of Washington

Language: English

Topic: Diabetes and associated disorders

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2106869746

FWCI: 8.568

Cites: 48

Cited by: 325

Related to: 10