Work

Optic pathway gliomas: a review

Year: 2013

Type: article

Abstract: Optic pathway gliomas account for 3-5% of all pediatric CNS tumors and represent the most common intrinsic optic nerve tumors. These tumors occur preferentially during the first decade of life and are particularly frequent in children with neurofibromatosis type 1. Although optic pathway gliomas are low-grade tumors, their behavior can be aggressive, and their management is often challenging. Their management includes observation, surgery, chemotherapy and radiation. The role of each modality is discussed as well as current and future developments in treatment, in particular targeted therapies that are currently being investigated.

Source: CNS Oncology

DOI: 10.2217/cns.12.47

Authors: Iris Fried, Uri Tabori, Tarik Tihan, Arun Reginald, Eric Bouffet

Institutions: University of Toronto, Hospital for Sick Children, University of California San Francisco Medical Center

Language: English

Topic: Glioma Diagnosis and Treatment

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2107058467

FWCI: 1.035

Cites: 122

Cited by: 129

Related to: 10