Work

Effects and applications of arthropod steroid hormones (ecdysteroids) in mammals

Year: 2006

Type: review

Abstract: Zooecdysteroids (arthropod steroid hormones) regulate the development of arthropods and probably many other invertebrates. Phytoecdysteroids are analogues occurring in a wide range of plant species, where they contribute to the deterrence of phytophagous invertebrates. The purpose of this short review is to summarise findings on the occurrence, metabolism and pharmacological effects of ecdysteroids in mammalian systems and to draw attention to their potential applications, particularly in gene-switch technology, where ecdysteroid analogues (steroidal and non-steroidal) can be used as effective and potent elicitors.

Source: Journal of Endocrinology

DOI: 10.1677/joe.1.06900

Authors: Laurence Dinan, René Lafont

Institutions: University of Exeter, Université Pierre-et-Marie-Curie

Language: English

Topic: Steroid Chemistry and Biochemistry

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

Funders: Leverhulme Trust, Ministère de l'Education Nationale, de l'Enseignement Supérieur et de la Recherche, Centre National de la Recherche Scientifique, Biotechnology and Biological Sciences Research Council

OpenAlex ID: W2107130601