Work

Complement Resistance Is Essential for Colonization of the Digestive Tract of Hirudo medicinalis by Aeromonas Strains

Year: 2003

Type: article

Abstract: From the crop of the medicinal leech, Hirudo medicinalis, only Aeromonas veronii bv. sobria can be cultured consistently. Serum-sensitive A. veronii mutants were unable to colonize H. medicinalis, indicating the importance of the mammalian complement system for this unusual simplicity. Complementation of one selected mutant restored its ability to colonize. Serum-sensitive mutants are the first mutant class with a colonization defect for this symbiosis.

Source: Applied and Environmental Microbiology

DOI: 10.1128/aem.69.7.4268-4271.2003

Authors: Thomas R. Braschler, Susana Merino, Juan M. Tomás, Joerg Graf

Institutions: University of Bern, Universitat de Barcelona, University of Connecticut

Language: English

Topic: Leech Biology and Applications

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

Open Access status: green

OpenAlex ID: W2107326865

FWCI: 1.071

Cites: 25

Cited by: 31

Related to: 10