Translational bioinformatics: linking knowledge across biological and clinical realms: Figure 1
Year: 2011
Type: article
Abstract: Nearly a decade since the completion of the first draft of the human genome, the biomedical community is positioned to usher in a new era of scientific inquiry that links fundamental biological insights with clinical knowledge. Accordingly, holistic approaches are needed to develop and assess hypotheses that incorporate genotypic, phenotypic, and environmental knowledge. This perspective presents translational bioinformatics as a discipline that builds on the successes of bioinformatics and health informatics for the study of complex diseases. The early successes of translational bioinformatics are indicative of the potential to achieve the promise of the Human Genome Project for gaining deeper insights to the genetic underpinnings of disease and progress toward the development of a new generation of therapies.
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $4,332
Awards: Semantic Approaches to Phenotypic Databases Analyses, San Diego Clinical and Translational Research Institute, G2143367978, iDASH: Integrating Data for Analysis, Anonymization, and Sharing, Enhancing Organism Based Disease Knowledge Via Name Based Taxonomic Intelligence, Integrating Microarray and Proteomic Data by Ontology-based Annotation, BioMediator: Biologic Data Integration&Analysis System, Institute for Translational Health Science (UL1), SCANNER: SCALABLE NATIONAL NETWORK FOR EFFECTIVENESS RESEARCH, Translational Research at The University of Chicago (UL1), Assessing quality of individual predictions in medical decision support systems, GeneClinics: Clinical Genetic Information Resource, University of Washington Biomedical Informatics and Data Science Research Training Program
OpenAlex ID: W2107720458