Antimicrobial activity of Lactobacillus helveticus strain 50P1.
Year: 2009
Type: article
Abstract: Few years ago the effectiveness of different Lactobacillus strains, with activity against different pathogens, was intensively studied. In particular, by producing metabolites such as acetic and lactic acid and thus lowering the pH, Lactobacillus strains inhibit the growth of bacterial pathogens and sometimes even kill them. In this study were included original Bulgarian dairy lactobacilli. The antibacterial activity against 8 test cultures and 8 clinical isolates was estimated by the agar diffusion method. We observed the inhibitory effect of growth of Bacillus subtilis, Bacillus alvei, Escherishia coli and Pseudomonas aeruginosa strains. The cells-free exponential cultures of non-neutralized (pH 3.9) and neutralized forms of the strain Lactobacillus sp. 50P1 showed highest activity. The active strain was identified as L. helveticus by classical and biochemical tests (API LAB 50CH kit). In addition to some technologically relevant properties the active strain 50P1 showed strong antibacterial effect against clinically isolated Pseudomonas aeruginosa and Bacillus alvei – an agricultural important bee pathogen. In conclusion, our results will form the basis for additional studies and possible further application of characterized L. helveticus 50P1 strain in clinical practice and/or veterinary medicine.
Language: English
Subfield: Food Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W97236597