Work

Genetic influences on insight problem solving: the role of catechol-O-methyltransferase (COMT) gene polymorphisms

Year: 2015
Type: article
Study design: Observational Study
Abstract: People may experience an "aha" moment, when suddenly realizing a solution of a puzzling problem. This experience is called insight problem solving. Several findings suggest that catecholamine-related genes may contribute to insight problem solving, among which the catechol-O-methyltransferase (COMT) gene is the most promising candidate. The current study examined 753 healthy individuals to determine the associations between 7 candidate single nucleotide polymorphisms on the COMT gene and insight problem-solving performance, while considering gender differences. The results showed that individuals carrying A allele of rs4680 or T allele of rs4633 scored significantly higher on insight problem-solving tasks, and the COMT gene rs5993883 combined with gender interacted with correct solutions of insight problems, specifically showing that this gene only influenced insight problem-solving performance in males. This study presents the first investigation of the genetic impact on insight problem solving and provides evidence that highlights the role that the COMT gene plays in insight problem solving.
Authors: Weili Jiang, Siyuan Shang, Yanjie Su
Institution: Peking University
Language: English
Field: Psychology
Open Access status: gold
Estimated APC paid: $3,801
OpenAlex ID: W2108746111
FWCI: 4.061
Cites: 59
Cited by: 33
Related to: 10