Work

Three‐dimensional structures and contexts associated with recurrent amino acid sequence patterns

Year: 1997

Type: article

Abstract: We have used cluster analysis to identify recurring sequence patterns that transcend protein family boundaries. A subset of these patterns occur predominantly in a single type of local structure in proteins. Here we characterize the three-dimensional structures and contexts in which these sequence patterns occur, with particular attention to the interactions responsible for their structural selectivity.

Source: Protein Science

DOI: 10.1002/pro.5560060723

Authors: Karen E Han, Christopher Bystroff, David Baker

Institutions: University of California, San Francisco, University of Washington

Language: English

Topic: Protein Structure and Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: National Science Foundation, David and Lucile Packard Foundation

Award: Science & Technology Center for Molecular Biotechnology