Development and Evaluation of a Calibrator Material for Nucleic Acid-Based Assays for Diagnosing Aspergillosis
Year: 2013
Type: article
Abstract: Twelve laboratories evaluated candidate material for an Aspergillus DNA calibrator. The DNA material was quantified using limiting-dilution analysis; the mean concentration was determined to be 1.73 × 10(10) units/ml. The calibrator can be used to standardize aspergillosis diagnostic assays which detect and/or quantify nucleic acid.
Source: Journal of Clinical Microbiology
DOI: 10.1128/jcm.00744-13
Authors: G. Marshall Lyon, Deborah Abdul-Ali, Juergen Loeffler, P. Lewis White, Brian Wickes, Monica L. Herrera, Barbara D. Alexander, Lindsey R. Baden, Cornelius Clancy, David Denning, M. Hong Nguyen, Michele Sugrue, L. Joseph Wheat, John R. Wingard, J. Peter Donnelly, Rosemary Barnes, Thomas F. Patterson, Angela M. Caliendo
Institutions: Emory University, University of Würzburg, University Hospital of Wales, Universitätsklinikum Würzburg, Public Health Wales, The University of Texas at San Antonio Health Science Center, South Texas Veterans Health Care System, Duke Medical Center, Brigham and Women's Hospital, Harvard University, University of Pittsburgh, University of Manchester, University of Florida, Radboud University Medical Center, Cardiff University
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2109147901