Low serum carotenoids are associated with a decline in walking speed in older women
Year: 2009
Type: article
Study design: Observational Study
Abstract: BACKGROUND AND OBJECTIVES: Walking speed is an important measure of physical performance that is predictive of disability and mortality. The relationship of dietary factors to changes in physical performance has not been well characterized in older adults. The aim was to determine whether total serum carotenoid concentrations, a marker for fruit and vegetable intake, and serum selenium are related to changes in walking speed in older women. SUBJECTS AND METHODS: The relationship between total serum carotenoids and selenium measured at baseline, 12, and 24 months follow-up and walking speed assessed at baseline and every six months for 36 months was examined in 687 moderately to severely disabled women, 65 years or older, living in the community. RESULTS: Mean total serum carotenoids were associated with mean walking speed over three years of follow-up (P = 0.0003) and rate of change of walking speed (P = 0.007) in multivariate linear regression models adjusting for age, body mass index, and chronic diseases. Mean serum selenium was associated with mean walking speed over three years of follow-up (P = 0.0003) but not with the rate of change of walking speed (P = 0.26). CONCLUSIONS: These findings suggest that a higher fruit and vegetable intake, as indicated by higher total serum carotenoid concentrations, may be protective against a decline in walking speed in older women.
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,450
Awards: G1699328781, GENERAL CLINICAL RESEARCH CENTER, G2524637290, G308843618, WOMEN'S HEALTH AND AGING, Pathogenesis of physical disability in Aging women, Oxidative stress and the pathogenesis of sarcopenia and disability in older women, The Baltimore Longitudinal Study Of Aging, G4629504595, RISK FACTORS FOR PHYSICAL DISABILITY IN AGING WOMEN
OpenAlex ID: W2109635915
