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Norepinephrine and Neural Interrupts

Year: 2005

Type: conference-paper

Abstract: Experimental data indicate that norepinephrine is critically involved in aspects of vigilance and attention. Previously, we considered the function of this neuromodulatory system on a time scale of minutes and longer, and suggested that it signals global uncertainty arising from gross changes in environmental contingencies. However, norepinephrine is also known to be activated phasically by familiar stimuli in well-learned tasks. Here, we extend our uncertainty-based treatment of norepinephrine to this phasic mode, proposing that it is involved in the detection and reaction to state uncertainty within a task. This role of norepinephrine can be understood through the metaphor of neural interrupts.

Source: TUbilio (Technical University of Darmstadt)

Authors: Peter Dayan, Angela J. Yu

Institutions: Gatsby Computational Neuroscience Unit, University College London, Princeton University

Language: English

Topic: Neural and Behavioral Psychology Studies

Subfield: Cognitive Neuroscience

Field: Neuroscience

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2109696716

FWCI: 2.304

Cites: 23

Cited by: 10

Related to: 10