Oxidative Decay of DNA
Year: 1997
Type: review
Abstract: The study of DNA oxidation has progressed from an exploratory phase, during which its basic biochemistry was established, into a field branching out into numerous areas. Early on, radiation biologists discovered that radiolysis of water generates oxygen free radicals, which are responsible for many of the consequences of irradiating living things. The characterization of radiation-induced oxidative DNA lesions, and the connection between radiation and cancer, caused a surge of interest in DNA oxidationper se and raised the possibility of DNA damage from biological oxidants.
Source: Journal of Biological Chemistry
Authors: Kenneth B. Beckman, Bruce N. Ames
Institution: University of California, Berkeley
Language: English
Topic: DNA Repair Mechanisms
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $3,430
OpenAlex ID: W2110223248